अमूर्त

Environmental chemical risk factors for Type 2 diabetes: an update

Anne P Starling & Jane A Hoppin

Increasing evidence suggests a role for environmental chemicals in the promotion of Type 2 diabetes. This review summarizes epidemiologic studies of environmental chemical exposures reported to be associated with Type 2 diabetes and insulin resistance. Chemicals are classified as having moderate, limited and insufficient degrees of evidence in support of a diabetes-promoting effect. Moderate evidence exists for diabetogenic effects of inorganic arsenic and persistent organic pollutants, including organochlorines, dioxins and polychlorinated biphenyls. Limited evidence supports a role for environmental tobacco smoke and ambient air pollution. Insufficient evidence is available regarding the potential effects of bisphenol A, phthalates, organophosphates and pyrethroids; most studies of such short-lived pollutants have been cross-sectional and do not demonstrate causality.

अस्वीकृति: इस सारांश का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया है और इसे अभी तक समीक्षा या सत्यापित नहीं किया गया है।