अमूर्त
Sevelamer hydrochloride: a calciumand metal-free phosphate binder
Anthony J Bleyer and James BalwitSevelamer hydrochloride is a nonabsorbed, calcium- and metal-free phosphate binder, used to bind phosphate and prevent phosphate accumulation in patients with kidney failure. Sevelamer hydrochloride has been an important alternative to calcium-based phosphate binders, because calcium-based binders result in increased gastrointestinal calcium absorption and a positive calcium burden in dialysis patients. Recent studies have shown that sevelamer hydrochloride slows the progression of cardiovascular calcification when compared with calcium-based binders – such decreases in cardiovascular calcification may potentially lead to a reduction in morbidity and mortality in dialysis patients.
अस्वीकृति: इस सारांश का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया है और इसे अभी तक समीक्षा या सत्यापित नहीं किया गया है।